CARDIOVASCULAR
GENE MAPPING CHALLENGES

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Cardio​​​​​vascular
Sub-challenges

  • Engineer cell “suicide switches” that may be able to selectively eliminate non-useful cells following a differentiation step (eg. residual hiPSCs leftover during the differentiation process).
  • Use autologous cells to ‘fix’ cardiomyopathies
  • Develop techniques for using gene editing to track cell survival.

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